DCN

Across TCGA cell cohorts, DCN mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible DCN-associated genes across cancer lineages are RBMXL3 and PNMA6E. Each is linked with DCN in more than 1 cancer types. Because this analysis shows association rather than direction, both DCN-to-partner and partner-to-DCN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBMXL3 grouped by DCN-low versus DCN-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCN→partner) and Y-score (partner→DCN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	RBMXL3 →	+0.406	+4.467	<.001	.004	3	1
SKIN	PNMA6E →	+0.053	+4.095	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

RBMXL3 by DCN expression — SKIN

Explore this box plot interactively →