DCLRE1C

Across TCGA pan-cancer cohorts, DCLRE1C RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of DCLRE1C’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where DCLRE1C RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DCLRE1C is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

KIRC, LIHC, and STAD are the cancer types where DCLRE1C tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DCLRE1C RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+0.389	<.001	10	view →
LIHC	Female	II,III,IV	+0.792	<.001	9	view →
STAD	All	All	+0.908	<.001	8	view →
COAD	Male	All	+0.487	<.001	8	view →
LUSC	All	II,III,IV	+0.435	<.001	7	view →
THCA	All	All	−0.275	<.001	7	view →
KIRP	All	IV	+0.929	.024	6	view →
BLCA	Female	III,IV	+0.704	.003	6	view →
LUAD	Male	All	+0.592	<.001	6	view →
UCEC	All	II,III,IV	+0.530	.011	6	view →
CHOL	Male	All	+2.008	<.001	5	view →
KICH	Female	All	−0.972	<.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

DCLRE1C–KIRC

Open the KIRC breakdown →