DCLRE1B

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DCLRE1B RNA expression is significantly associated with the protein abundance of many other proteins, with 14,609 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DCLRE1B-associated proteins across cancer lineages are CDC20_T70, RRM2, and MCM2. Each is linked with DCLRE1B in more than 8 cancer types. Because this analysis shows association rather than direction, both DCLRE1B-to-partner and partner-to-DCLRE1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCLRE1B versus CDC20_T70 in GBM, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DCLRE1B→partner) and Y-score (partner→DCLRE1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCDC20_T70 →+1.372+0.490<.001<.00139
LUADRRM2 →+0.837+0.533<.001<.00139
GBMMCM2 →+0.648+0.263<.001<.00139
GBMMCM3 →+0.638+0.272<.001<.00139
GBMMCM4 →+0.965+0.570<.001<.00139
GBMMCM5 →+0.630+0.294<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,609 associations by consensus.

DCLRE1B vs CDC20_T70 — GBM

Per-sample scatter of DCLRE1B vs CDC20_T70 in GBM (Pearson r = 0.61).

Explore this scatter interactively →

Exploration