Across TCGA cell cohorts, DCLRE1A mutation is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DCLRE1A-associated genes across cancer lineages are OR7G3, PRR30, and OR2B2. Each is linked with DCLRE1A in more than 1 cancer types. Because this analysis shows association rather than direction, both DCLRE1A-to-partner and partner-to-DCLRE1A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCLRE1A→partner) and Y-score (partner→DCLRE1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR7G3 →	+0.047	+4.643	<.001	.004	3	2
LUNG_NSCLC_LUAD	PRR30 →	+0.011	+4.189	<.001	.002	3	2
KIDNEY	OR2B2 →	+0.036	+5.000	<.001	.005	3	1
KIDNEY	MTRNR2L10 →	+0.013	+5.000	<.001	.005	3	1
OESOPHAGUS	OR13C2 →	+0.033	+4.906	<.001	.006	3	1
LUNG_SCLC	CCL24 →	+0.189	+4.269	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Exploration

DCLRE1A survival (RNA) · tumor vs normal (RNA) · all DCLRE1A data types