DCLK3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DCLK3 protein abundance is significantly associated with the RNA expression of many other genes, with 434 significant associations in total. OV shows the largest number of these associations.

The most reproducible DCLK3-associated genes across cancer lineages are PPP4R3A, NAA10, and CDK16. Each is linked with DCLK3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCLK3-to-partner and partner-to-DCLK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCLK3 versus PPP4R3A in OV, with a Pearson correlation of -0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCLK3→partner) and Y-score (partner→DCLK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVPPP4R3A →-0.660-2.287.003.00231
OVNAA10 →-0.819-2.287.002.00231
OVCDK16 →-0.515-2.287.004.00231
OVMCM4 →-0.780-1.933.001<.00131
OVDYRK1B →-1.534-2.287.002.00231
OVPLPPR2 →-0.942-2.287.006.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 434 associations by consensus.

DCLK3 vs PPP4R3A — OV

Per-sample scatter of DCLK3 vs PPP4R3A in OV (Pearson r = -0.69).

Explore this scatter interactively →

Exploration