DCLK3

Across TCGA cell cohorts, DCLK3 RNA expression is significantly associated with the go_rna of many other GO terms, with 646 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible DCLK3-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, Endoplasmic reticulum to Golgi vesicle-mediated transport, and RNA catabolic process. Each is linked with DCLK3 in more than 6 cancer types. Because this analysis shows association rather than direction, both DCLK3-to-partner and partner-to-DCLK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA catabolic process grouped by DCLK3-low versus DCLK3-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DCLK3→partner) and Y-score (partner→DCLK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Nuclear-transcribed mRNA catabolic process →	+0.047	+0.034	.009	.007	3	7
UPPER_AERODIGESTIVE_TRACT	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.063	+0.010	<.001	.006	3	7
BLOOD_Leukemia	RNA catabolic process →	+0.033	+0.066	<.001	.006	3	7
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.078	+0.031	<.001	.002	3	7
OVARY	Regulation of myoblast fusion →	+0.084	+0.031	<.001	.002	3	6
UPPER_AERODIGESTIVE_TRACT	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.058	+0.010	.002	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 646 associations by consensus.

Nuclear-transcribed mRNA catabolic process by DCLK3 expression — OESOPHAGUS

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