DCLK2

Across TCGA patient cohorts, DCLK2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,872 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DCLK2-associated genes across cancer lineages are JAM2, TIMP3, and MPDZ. Each is linked with DCLK2 in more than 5 cancer types. Because this analysis shows association rather than direction, both DCLK2-to-partner and partner-to-DCLK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCLK2 versus JAM2 in CCRCC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCLK2→partner) and Y-score (partner→DCLK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	JAM2 →	+0.767	+0.415	<.001	<.001	3	6
UCEC	TIMP3 →	+1.666	+0.692	<.001	<.001	3	5
OV	MPDZ →	+0.990	+0.347	<.001	.005	3	5
OV	ACTA2 →	+1.762	+0.490	<.001	<.001	3	5
BRCA	CNN3 →	+0.844	+0.507	<.001	<.001	3	5
OV	KCNJ8 →	+0.850	+0.398	<.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,872 associations by consensus.

DCLK2 vs JAM2 — CCRCC

Explore this scatter interactively →