DCLK2

Across TCGA cell cohorts, DCLK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,128 significant associations in total. CNS shows the largest number of these associations.

The most reproducible DCLK2-associated GO terms across cancer lineages are Cell division, Cytoskeleton-dependent cytokinesis, and Positive regulation of protein localization to centrosome. Each is linked with DCLK2 in more than 12 cancer types. Because this analysis shows association rather than direction, both DCLK2-to-partner and partner-to-DCLK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell division grouped by DCLK2-low versus DCLK2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DCLK2→partner) and Y-score (partner→DCLK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Cell division →	+0.084	+1.783	.001	.001	3	13
LUNG_NSCLC_LUSC	Cytoskeleton-dependent cytokinesis →	+0.070	+1.419	<.001	.005	3	12
URINARY_TRACT	Positive regulation of protein localization to centrosome →	+0.113	+1.053	<.001	.001	3	11
SKIN	Regulation of G1/S transition of mitotic cell cycle →	+0.059	+0.838	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Cytokinesis →	+0.071	+1.674	<.001	<.001	3	11
SKIN	Regulation of cell cycle G1/S phase transition →	+0.054	+0.921	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,128 associations by consensus.

Cell division by DCLK2 expression — LIVER

Explore this box plot interactively →