DCLK1

Across TCGA patient cohorts, DCLK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,872 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DCLK1-associated proteins across cancer lineages are DCLK1_S313, DCLK1_S330, and PHLDB1. Each is linked with DCLK1 in more than 7 cancer types. Because this analysis shows association rather than direction, both DCLK1-to-partner and partner-to-DCLK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCLK1 versus DCLK1_S313 in CCRCC, with a Pearson correlation of 0.80.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DCLK1→partner) and Y-score (partner→DCLK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	DCLK1_S313 →	+1.414	+1.366	<.001	<.001	3	8
BRCA	DCLK1_S330 →	+1.772	+2.306	<.001	<.001	3	8
COAD	PHLDB1 →	+0.302	+0.393	<.001	<.001	3	7
BRCA	DCLK1_S172 →	+1.365	+1.538	<.001	<.001	3	7
OV	DCLK1_S307 →	+1.130	+0.605	<.001	<.001	3	7
CCRCC	DCLK1_S332 →	+1.315	+2.191	.004	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,872 associations by consensus.

DCLK1 vs DCLK1_S313 — CCRCC

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