DCK

Across TCGA pan-cancer cohorts, DCK Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated DCK data layer compared with 25 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher DCK Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated DCK expression acts as an unfavorable survival marker.

HNSC, KIRP, and GBM are the cancer types where DCK Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.231	0.661	.030	15	view →
KIRP	OS	Median	All	0.101	0.688	.002	12	view →
GBM	OS	Median	All	0.101	0.413	.035	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

DCK–HNSC (OS)

Open the HNSC breakdown →