DCK

Across TCGA patient cohorts, DCK RNA expression is significantly associated with the protein abundance of many other proteins, with 11,329 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DCK-associated proteins across cancer lineages are TPX2_S486, NUF2_S247, and NCAPG. Each is linked with DCK in more than 4 cancer types. Because this analysis shows association rather than direction, both DCK-to-partner and partner-to-DCK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCK versus TPX2_S486 in PDAC, with a Pearson correlation of 0.71.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DCK→partner) and Y-score (partner→DCK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TPX2_S486 →	+1.753	+0.736	.007	.002	3	5
UCEC	NUF2_S247 →	+1.101	+0.678	<.001	<.001	3	5
LSCC	NCAPG →	+0.464	+0.495	<.001	<.001	3	5
OV	NCAPG_S674 →	+0.969	+0.545	.002	.002	3	5
COAD	NCAPH →	+0.489	+0.440	.007	<.001	3	5
LSCC	SMC2 →	+0.498	+0.493	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,329 associations by consensus.

DCK vs TPX2_S486 — PDAC

Explore this scatter interactively →