DCK

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DCK protein abundance is significantly associated with the RNA expression of many other genes, with 10,742 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCK-associated genes across cancer lineages are CXCR2P1, CD48, and FAM78A. Each is linked with DCK in more than 7 cancer types. Because this analysis shows association rather than direction, both DCK-to-partner and partner-to-DCK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCK versus CXCR2P1 in UCEC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCK→partner) and Y-score (partner→DCK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCXCR2P1 →+1.418+0.335<.001<.00138
UCECCD48 →+0.879+0.250.001.00937
BRCAFAM78A →+0.650+0.379<.001<.00137
OVADAMDEC1 →+2.117+0.564<.001.00728
OVTACC3 →+1.257+0.583<.001<.00137
COADPTPN7 →+0.832+0.232.001.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,742 associations by consensus.

DCK vs CXCR2P1 — UCEC

Per-sample scatter of DCK vs CXCR2P1 in UCEC (Pearson r = 0.49).

Explore this scatter interactively →

Exploration