DCK

Across TCGA patient cohorts, DCK mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCK-associated genes across cancer lineages are EGFR_pY1068 and p62 Lck ligand. Each is linked with DCK in more than 1 cancer types. Because this analysis shows association rather than direction, both DCK-to-partner and partner-to-DCK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by DCK-low versus DCK-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCK→partner) and Y-score (partner→DCK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.319	-3.169	.020	.020	3	1
UCEC	p62 Lck ligand →	+0.482	+3.169	.006	.020	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

EGFR_pY1068 by DCK expression — UCEC

Explore this box plot interactively →