Across TCGA patient cohorts, DCHS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,070 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DCHS2-associated proteins across cancer lineages are MFAP2, TLN2, and NFIX. Each is linked with DCHS2 in more than 5 cancer types. Because this analysis shows association rather than direction, both DCHS2-to-partner and partner-to-DCHS2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DCHS2→partner) and Y-score (partner→DCHS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MFAP2 →	+0.547	+0.116	.001	.001	3	6
HNSC	TLN2 →	+0.651	+0.688	<.001	.002	3	6
BRCA	NFIX →	+0.626	+0.413	<.001	<.001	3	5
LSCC	PDLIM4 →	+0.612	+0.578	<.001	<.001	3	5
HNSC	PHLDB1 →	+0.518	+0.823	<.001	<.001	3	5
CCRCC	AMPD2 →	+0.330	+0.829	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,070 associations by consensus.

Exploration

DCHS2 survival (RNA) · tumor vs normal (RNA) · all DCHS2 data types