Across TCGA patient cohorts, DCHS2 protein abundance is significantly associated with the RNA expression of many other genes, with 639 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible DCHS2-associated genes across cancer lineages are TNNT1, PUDP, and SLC16A2. Each is linked with DCHS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCHS2-to-partner and partner-to-DCHS2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCHS2→partner) and Y-score (partner→DCHS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TNNT1 →	+2.413	+1.130	<.001	<.001	3	1
HNSC	PUDP →	+0.593	+1.097	.004	.003	3	1
HNSC	SLC16A2 →	+1.227	+1.219	<.001	<.001	3	1
HNSC	PPP1R3A →	+1.131	+0.783	.008	.006	3	1
HNSC	MFSD14A →	+0.581	+0.922	.002	.007	3	1
HNSC	COX6A2 →	+1.841	+0.920	.009	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 639 associations by consensus.

Exploration

DCHS2 survival (RNA) · tumor vs normal (RNA) · all DCHS2 data types