DCBLD2

Across TCGA patient cohorts, DCBLD2 mutation is significantly associated with the RNA expression of many other genes, with 5,301 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCBLD2-associated genes across cancer lineages are TRDJ2, GEMIN8P3, and RAB9BP1. Each is linked with DCBLD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCBLD2-to-partner and partner-to-DCBLD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRDJ2 grouped by DCBLD2-low versus DCBLD2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCBLD2→partner) and Y-score (partner→DCBLD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TRDJ2 →	+1.240	+4.341	<.001	.003	3	2
BRCA	GEMIN8P3 →	+0.037	+4.431	.003	.008	3	2
HNSC	RAB9BP1 →	+0.080	+6.407	<.001	<.001	3	2
HNSC	SDHCP1 →	+0.111	+5.266	<.001	.001	3	2
COAD	MIR5707 →	+0.639	+3.285	<.001	.003	3	2
CESC	MTND4LP20 →	+0.168	+7.164	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,301 associations by consensus.

TRDJ2 by DCBLD2 expression — BRCA

Explore this box plot interactively →