DCBLD2

Across TCGA cell cohorts, DCBLD2 mutation is significantly associated with the RNA expression of many other genes, with 62 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DCBLD2-associated genes across cancer lineages are GALR3, RHOXF1, and NPHS2. Each is linked with DCBLD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCBLD2-to-partner and partner-to-DCBLD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GALR3 grouped by DCBLD2-low versus DCBLD2-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCBLD2→partner) and Y-score (partner→DCBLD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	GALR3 →	+0.057	+3.584	<.001	.009	3	2
URINARY_TRACT	RHOXF1 →	+0.164	+3.643	<.001	.007	3	1
URINARY_TRACT	NPHS2 →	+0.150	+4.044	.001	.001	3	1
URINARY_TRACT	TINAG →	+2.959	+3.584	<.001	.008	3	1
URINARY_TRACT	PRR23A →	+0.022	+3.584	<.001	.005	3	1
URINARY_TRACT	SPINK13 →	+1.101	+3.523	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

GALR3 by DCBLD2 expression — URINARY_TRACT

Explore this box plot interactively →