DCAKD

Across TCGA pan-cancer cohorts, DCAKD mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated DCAKD data layer compared with 28 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher DCAKD mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated DCAKD expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

HNSC, CCRCC, and LSCC are the cancer types where DCAKD mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.938	0.993	.018	16	view →
CCRCC	DFS	Quartile	All	0.947	0.600	.006	5	view →
LSCC	OS	Median	III,IV	0.737	0.956	.025	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

DCAKD–HNSC (OS)

Open the HNSC breakdown →