Across TCGA patient cohorts, DCAF8L2 mutation is significantly associated with the RNA expression of many other genes, with 4,770 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCAF8L2-associated genes across cancer lineages are CMC2, BCCIP, and NPRL2. Each is linked with DCAF8L2 in more than 3 cancer types. Because this analysis shows association rather than direction, both DCAF8L2-to-partner and partner-to-DCAF8L2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF8L2→partner) and Y-score (partner→DCAF8L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CMC2 →	+0.369	+1.621	<.001	<.001	3	4
UCEC	BCCIP →	+0.327	+1.830	<.001	<.001	3	4
UCEC	NPRL2 →	+0.234	+2.780	.001	<.001	3	4
UCEC	SET →	+0.349	+1.220	.002	.002	3	4
UCEC	MCMBP →	+0.331	+1.531	.002	<.001	3	4
UCEC	CKLF →	+0.469	+1.478	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,770 associations by consensus.

Exploration

DCAF8L2 survival (RNA) · tumor vs normal (RNA) · all DCAF8L2 data types