Across TCGA cell cohorts, DCAF8L2 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. CNS shows the largest number of these associations.

The most reproducible DCAF8L2-associated genes across cancer lineages are CRISP1, IFNA14, and TPRX1. Each is linked with DCAF8L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCAF8L2-to-partner and partner-to-DCAF8L2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF8L2→partner) and Y-score (partner→DCAF8L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CRISP1 →	+0.013	+5.321	<.001	.005	3	2
SOFT_TISSUE	IFNA14 →	+0.032	+5.369	<.001	.004	3	1
BLOOD_Lymphoma	TPRX1 →	+0.006	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	GRXCR1 →	+0.029	+5.643	<.001	.002	3	1
BREAST	OR2T2 →	+0.012	+5.169	<.001	.005	3	1
LUNG_SCLC	AVP →	+0.729	+2.906	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

DCAF8L2 survival (RNA) · tumor vs normal (RNA) · all DCAF8L2 data types