DCAF8

Across TCGA patient cohorts, DCAF8 mutation is significantly associated with the RNA expression of many other genes, with 2,458 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCAF8-associated genes across cancer lineages are RN7SKP72, MED15P4, and RNU6-503P. Each is linked with DCAF8 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCAF8-to-partner and partner-to-DCAF8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP72 grouped by DCAF8-low versus DCAF8-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF8→partner) and Y-score (partner→DCAF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SKP72 →	+0.219	+5.680	<.001	.003	3	2
LUAD	MED15P4 →	+0.625	+4.044	<.001	.002	3	2
LUAD	RNU6-503P →	+0.524	+4.044	<.001	.002	3	2
LUAD	MIR4445 →	+0.518	+4.584	<.001	.005	3	2
UCEC	RNU6-1069P →	+0.456	+1.453	<.001	.006	3	2
SKCM	TUBB8P3 →	+0.071	+5.097	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,458 associations by consensus.

RN7SKP72 by DCAF8 expression — SKCM

Explore this box plot interactively →