DCAF7

Across TCGA pan-cancer cohorts, DCAF7 mass-spec protein differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of DCAF7’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where DCAF7 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types DCAF7 is over-expressed in tumor.

LUAD, COAD, and LSCC are the cancer types where DCAF7 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DCAF7 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	II,III,IV	+0.275	<.001	9	view →
COAD	Female	III,IV	+0.154	<.001	9	view →
LSCC	Male	All	+0.322	<.001	8	view →
PDAC	Male	All	+0.383	<.001	6	view →
OV	All	All	+0.306	.022	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

DCAF7–LUAD

Open the LUAD breakdown →