DCAF4L1

Across TCGA patient cohorts, DCAF4L1 mutation is significantly associated with the RNA expression of many other genes, with 4,072 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCAF4L1-associated genes across cancer lineages are NOL4L, RNU6-1127P, and RN7SL25P. Each is linked with DCAF4L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DCAF4L1-to-partner and partner-to-DCAF4L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NOL4L grouped by DCAF4L1-low versus DCAF4L1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF4L1→partner) and Y-score (partner→DCAF4L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	NOL4L →	-0.945	-2.775	<.001	.003	3	3
COAD	RNU6-1127P →	+0.261	+3.306	<.001	.003	3	3
CESC	RN7SL25P →	+0.279	+4.567	<.001	.001	3	2
LUSC	CTBP2P9 →	+0.032	+4.882	<.001	.005	3	2
UCEC	SYNGR1 →	-0.588	-2.034	<.001	<.001	3	2
UCEC	GZMH →	+0.978	+2.306	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,072 associations by consensus.

NOL4L by DCAF4L1 expression — SKCM

Explore this box plot interactively →