DCAF4L1

Across TCGA cell cohorts, DCAF4L1 mutation is significantly associated with the RNA expression of many other genes, with 164 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DCAF4L1-associated genes across cancer lineages are MYF6, CES5A, and CLLU1-AS1. Each is linked with DCAF4L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCAF4L1-to-partner and partner-to-DCAF4L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYF6 grouped by DCAF4L1-low versus DCAF4L1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF4L1→partner) and Y-score (partner→DCAF4L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	MYF6 →	+1.059	+4.887	<.001	.009	3	2
URINARY_TRACT	CES5A →	+0.016	+5.087	<.001	.004	3	1
URINARY_TRACT	CLLU1-AS1 →	+0.113	+5.087	<.001	.004	3	1
URINARY_TRACT	CFAP97D2 →	+0.043	+5.087	<.001	.004	3	1
LARGE_INTESTINE	FBXL4 →	+0.624	+3.212	<.001	.006	3	1
LARGE_INTESTINE	BCAS2 →	+0.764	+3.212	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 164 associations by consensus.

MYF6 by DCAF4L1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →