DCAF4L1

Across TCGA cell cohorts, DCAF4L1 mutation is significantly associated with the mutation status of many other genes, with 3,904 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DCAF4L1-associated genes across cancer lineages are WAPL, WIPI1, and NOS1. Each is linked with DCAF4L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DCAF4L1-to-partner and partner-to-DCAF4L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WAPL grouped by DCAF4L1-low versus DCAF4L1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF4L1→partner) and Y-score (partner→DCAF4L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	WAPL →	+2.269	+3.029	<.001	<.001	1	3
LARGE_INTESTINE	WIPI1 →	+4.217	+2.865	.007	.007	1	3
LARGE_INTESTINE	NOS1 →	+2.172	+3.479	<.001	<.001	1	3
LARGE_INTESTINE	ZC3H6 →	+2.632	+2.632	.003	.003	1	3
LARGE_INTESTINE	OGA →	+4.632	+3.159	<.001	<.001	1	3
LUNG_NSCLC_LUAD	NCOA6 →	+4.187	+5.000	.008	.008	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,904 associations by consensus.

WAPL by DCAF4L1 expression — LARGE_INTESTINE

Explore this box plot interactively →