DCAF17

Across TCGA patient cohorts, DCAF17 mutation is significantly associated with the RNA expression of many other genes, with 770 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCAF17-associated genes across cancer lineages are RNU6-1085P, SDR42E1P1, and FAM236A. Each is linked with DCAF17 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCAF17-to-partner and partner-to-DCAF17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1085P grouped by DCAF17-low versus DCAF17-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF17→partner) and Y-score (partner→DCAF17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-1085P →	+0.404	+5.070	<.001	.001	3	2
BRCA	SDR42E1P1 →	+0.047	+7.473	<.001	.007	3	1
BRCA	FAM236A →	+0.049	+7.473	<.001	.007	3	1
BRCA	MIR8081 →	+0.484	+4.841	<.001	.006	3	1
BLCA	RN7SL774P →	+0.231	+3.982	<.001	.006	3	1
BLCA	MIR6892 →	+0.231	+6.048	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 770 associations by consensus.

RNU6-1085P by DCAF17 expression — LUSC

Explore this box plot interactively →