DCAF16

Across TCGA cell cohorts, DCAF16 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,028 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DCAF16-associated GO terms across cancer lineages are Positive regulation of organelle assembly, Regulation of DNA repair, and Transcription pausing by RNA polymerase II. Each is linked with DCAF16 in more than 15 cancer types. Because this analysis shows association rather than direction, both DCAF16-to-partner and partner-to-DCAF16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of organelle assembly grouped by DCAF16-low versus DCAF16-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF16→partner) and Y-score (partner→DCAF16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of organelle assembly →	+0.063	+1.323	<.001	<.001	3	16
BONE	Regulation of DNA repair →	+0.075	+0.809	.007	.004	3	15
BONE	Transcription pausing by RNA polymerase II →	+0.152	+0.802	<.001	<.001	3	15
OVARY	Heterochromatin organization →	+0.079	+0.760	<.001	<.001	3	14
LARGE_INTESTINE	Protein K11-linked ubiquitination →	+0.094	+0.721	<.001	<.001	3	14
LARGE_INTESTINE	Positive regulation of cilium assembly →	+0.073	+0.624	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,028 associations by consensus.

Positive regulation of organelle assembly by DCAF16 expression — URINARY_TRACT

Explore this box plot interactively →