DCAF15

Across TCGA pan-cancer cohorts, DCAF15 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DCAF15 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher DCAF15 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated DCAF15 expression acts as an unfavorable survival marker, although some lineages such as LSCC and HNSC show a favorable association.

LSCC, HNSC, and LUAD are the cancer types where DCAF15 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Tertile	II,III,IV	1.000	0.603	.002	38	view →
HNSC	OS	Median	All	1.000	0.347	.040	6	view →
LUAD	DFS	Quartile	All	1.000	0.371	.021	4	view →
UCEC	DFS	Median	III,IV	0.904	0.445	.037	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DCAF15–LSCC (OS)

Open the LSCC breakdown →