DCAF15

Across TCGA cell cohorts, DCAF15 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,721 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DCAF15-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Regulation of anaphase-promoting complex-dependent catabolic process, and Positive regulation of anaphase-promoting complex-dependent catabolic process. Each is linked with DCAF15 in more than 17 cancer types. Because this analysis shows association rather than direction, both DCAF15-to-partner and partner-to-DCAF15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by DCAF15-low versus DCAF15-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF15→partner) and Y-score (partner→DCAF15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of DNA metabolic process →	+0.053	+0.583	<.001	<.001	3	18
BONE	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.245	+1.106	<.001	<.001	3	18
BONE	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.187	+0.926	<.001	<.001	3	18
BONE	Mitotic chromosome condensation →	+0.158	+0.696	.003	<.001	3	17
BONE	Regulation of DNA-templated DNA replication →	+0.153	+0.779	.001	.002	3	17
BONE	Spindle organization →	+0.118	+0.767	.001	.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,721 associations by consensus.

Positive regulation of DNA metabolic process by DCAF15 expression — SOFT_TISSUE

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