DCAF15

Across TCGA cell cohorts, DCAF15 protein abundance is significantly associated with the go_rna of many other GO terms, with 907 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DCAF15-associated GO terms across cancer lineages are Choline metabolic process, L-alanine transmembrane transport, and Cellular response to lithium ion. Each is linked with DCAF15 in more than 3 cancer types. Because this analysis shows association rather than direction, both DCAF15-to-partner and partner-to-DCAF15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Choline metabolic process grouped by DCAF15-low versus DCAF15-high in BLOOD_Leukemia.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF15→partner) and Y-score (partner→DCAF15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Choline metabolic process →	-1.357	-2.055	.003	<.001	3	4
OESOPHAGUS	L-alanine transmembrane transport →	+0.168	+2.341	.003	.007	3	4
CNS	Cellular response to lithium ion →	+0.170	+1.393	<.001	.007	3	3
LUNG_SCLC	Cellular response to cell-matrix adhesion →	-0.305	-1.524	<.001	<.001	3	3
BLOOD_Leukemia	Cardiac left ventricle morphogenesis →	-0.341	-2.616	<.001	<.001	3	3
BLOOD_Leukemia	Positive regulation of phosphorylation →	+0.047	+2.200	.004	.003	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 907 associations by consensus.

Choline metabolic process by DCAF15 expression — BLOOD_Leukemia

Explore this box plot interactively →