DCAF15

Across TCGA cell cohorts, DCAF15 mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DCAF15-associated genes across cancer lineages are OR10Q1, UNCX, and SHD. Each is linked with DCAF15 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCAF15-to-partner and partner-to-DCAF15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10Q1 grouped by DCAF15-low versus DCAF15-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF15→partner) and Y-score (partner→DCAF15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR10Q1 →	+0.110	+3.920	.001	.005	3	2
URINARY_TRACT	UNCX →	+0.013	+5.087	<.001	.004	3	1
BLOOD_Leukemia	SHD →	+0.638	+3.321	.001	.009	3	1
BLOOD_Leukemia	ITK →	+2.818	+3.331	<.001	.008	3	1
BLOOD_Leukemia	NGF →	+0.260	+2.857	<.001	.006	3	1
BLOOD_Leukemia	RORC →	+1.134	+3.328	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

OR10Q1 by DCAF15 expression — LARGE_INTESTINE

Explore this box plot interactively →