DCAF13

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DCAF13 mutation is significantly associated with the RNA expression of many other genes, with 2,957 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCAF13-associated genes across cancer lineages are RN7SL134P, SPRING1P1, and MTCO1P56. Each is linked with DCAF13 in more than 2 cancer types. Because this analysis shows association rather than direction, both DCAF13-to-partner and partner-to-DCAF13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by DCAF13-low versus DCAF13-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF13→partner) and Y-score (partner→DCAF13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRN7SL134P →+0.212+4.204<.001<.00133
COADSPRING1P1 →+0.081+4.399<.001.00633
COADMTCO1P56 →+0.235+4.595<.001.00432
UCECPLCB3 →+0.476+2.386<.001<.00132
UCECCLEC1A →-0.292-3.936.009<.00132
UCECBAG3 →+0.524+3.764.003<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,957 associations by consensus.

RN7SL134P by DCAF13 expression — COAD

Box plot of RN7SL134P in DCAF13-low vs DCAF13-high samples in COAD.

Explore this box plot interactively →

Exploration