DCAF13

Across TCGA patient cohorts, DCAF13 mutation is significantly associated with the immune_cell of many other genes, with 17 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible DCAF13-associated genes across cancer lineages are CLP, Erythrocytes, and Skeletal muscle. Each is linked with DCAF13 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCAF13-to-partner and partner-to-DCAF13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLP grouped by DCAF13-low versus DCAF13-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF13→partner) and Y-score (partner→DCAF13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	CLP →	+0.119	+2.187	<.001	.034	3	2
LUSC	Erythrocytes →	+0.017	+2.282	.019	.015	3	2
LUSC	Skeletal muscle →	+0.036	+2.232	.007	.032	3	2
LUSC	Smooth muscle →	-0.142	-3.146	<.001	.019	3	2
UCEC	Endothelial cells →	-0.045	-2.764	.001	<.001	3	2
UCEC	lymphatic Endothelial cells →	-0.028	-4.138	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

CLP by DCAF13 expression — LUSC

Explore this box plot interactively →