Across TCGA patient cohorts, DCAF12L2 mutation is significantly associated with the total protein of many other genes, with 64 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCAF12L2-associated genes across cancer lineages are PDK1, A-Raf_pS299, and Caspase-7-cleavedD198. Each is linked with DCAF12L2 in more than 2 cancer types. Because this analysis shows association rather than direction, both DCAF12L2-to-partner and partner-to-DCAF12L2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF12L2→partner) and Y-score (partner→DCAF12L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	PDK1 →	-0.135	-3.000	.021	.035	3	3
UCEC	A-Raf_pS299 →	-0.094	-1.514	.004	.014	3	3
COAD	Caspase-7-cleavedD198 →	+0.979	+2.008	.002	.018	3	3
UCEC	4E-BP1 →	+0.324	+2.662	<.001	<.001	3	3
COAD	NF2 →	+0.164	+3.012	.036	.018	3	3
LUSC	PKC-b-II_pS660 →	+0.363	+3.331	.017	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 64 associations by consensus.

Exploration

DCAF12L2 survival (RNA) · tumor vs normal (RNA) · all DCAF12L2 data types