DCAF11

Across TCGA pan-cancer cohorts, DCAF11 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated DCAF11 data layer compared with 20 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher DCAF11 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DCAF11 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LSCC show a favorable association.

CCRCC, LUAD, and LSCC are the cancer types where DCAF11 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	All	0.986	0.557	<.001	27	view →
LUAD	DFS	Tertile	II,III,IV	0.416	0.905	.004	11	view →
LSCC	OS	Median	II,III,IV	0.914	0.644	.001	11	view →
PDAC	OS	Tertile	All	0.560	0.370	.033	2	view →
HNSC	OS	Median	IV	0.846	0.617	.024	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

DCAF11–CCRCC (DFS)

Open the CCRCC breakdown →