DCAF1

Across TCGA pan-cancer cohorts, DCAF1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated DCAF1 data layer compared with 22 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher DCAF1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DCAF1 expression acts as an unfavorable survival marker, although some lineages such as COAD and CCRCC show a favorable association.

COAD, CCRCC, and PDAC are the cancer types where DCAF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	II,III,IV	1.000	0.901	.031	30	view →
CCRCC	DFS	Quartile	All	1.000	0.378	.005	17	view →
PDAC	OS	Quartile	II,III,IV	0.762	0.907	.008	12	view →
LSCC	DFS	Quartile	All	0.998	0.846	.032	7	view →
LUAD	OS	Quartile	II,III,IV	1.000	0.871	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

DCAF1–COAD (DFS)

Open the COAD breakdown →