DCAF1

Across TCGA cell cohorts, DCAF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,616 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DCAF1-associated GO terms across cancer lineages are Protein-DNA complex disassembly, Nuclear transport, and DNA-templated DNA replication. Each is linked with DCAF1 in more than 17 cancer types. Because this analysis shows association rather than direction, both DCAF1-to-partner and partner-to-DCAF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-DNA complex disassembly grouped by DCAF1-low versus DCAF1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF1→partner) and Y-score (partner→DCAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein-DNA complex disassembly →	+0.180	+0.558	<.001	.004	3	18
SOFT_TISSUE	Nuclear transport →	+0.082	+0.779	<.001	.001	3	18
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.147	+1.254	<.001	<.001	3	18
BONE	DNA replication initiation →	+0.175	+0.709	.002	<.001	3	18
SOFT_TISSUE	Nucleocytoplasmic transport →	+0.082	+0.779	<.001	.001	3	18
SOFT_TISSUE	Mitotic spindle elongation →	+0.240	+0.720	<.001	.002	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,616 associations by consensus.

Protein-DNA complex disassembly by DCAF1 expression — OESOPHAGUS

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