Across TCGA patient cohorts, DBX2 mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DBX2-associated genes across cancer lineages are Bim, CDK1, and C-Raf. Each is linked with DBX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DBX2-to-partner and partner-to-DBX2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DBX2→partner) and Y-score (partner→DBX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Bim →	-0.314	-3.700	.010	.001	3	1
SKCM	CDK1 →	+0.208	+2.321	.009	.033	3	1
SKCM	C-Raf →	-0.176	-3.000	.006	.035	3	1
SKCM	53BP1 →	-0.522	-2.584	.002	.011	3	1
UCEC	ERK2 →	+0.211	+2.000	.015	.032	3	1
UCEC	FoxM1 →	+0.231	+2.700	.047	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

DBX2 survival (RNA) · tumor vs normal (RNA) · all DBX2 data types