DBT

Across TCGA patient cohorts, DBT RNA expression is significantly associated with the protein abundance of many other proteins, with 14,356 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DBT-associated proteins across cancer lineages are NRBF2, AGL, and CKAP4_S26. Each is linked with DBT in more than 5 cancer types. Because this analysis shows association rather than direction, both DBT-to-partner and partner-to-DBT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DBT versus NRBF2 in GBM, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DBT→partner) and Y-score (partner→DBT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NRBF2 →	-0.395	-0.430	<.001	<.001	3	6
BRCA	AGL →	+0.384	+0.312	.001	.001	3	6
BRCA	CKAP4_S26 →	-0.741	-0.407	<.001	<.001	3	5
BRCA	HSPA13 →	-0.421	-0.392	<.001	<.001	3	5
LSCC	MANF →	-0.578	-0.469	<.001	<.001	3	5
HNSC	TXNDC5 →	-0.608	-0.461	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,356 associations by consensus.

DBT vs NRBF2 — GBM

Explore this scatter interactively →