DBT

Across TCGA patient cohorts, DBT protein abundance is significantly associated with the RNA expression of many other genes, with 10,687 significant associations in total. COAD shows the largest number of these associations.

The most reproducible DBT-associated genes across cancer lineages are LINC01943, EMP3, and DSE. Each is linked with DBT in more than 8 cancer types. Because this analysis shows association rather than direction, both DBT-to-partner and partner-to-DBT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DBT versus LINC01943 in GBM, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DBT→partner) and Y-score (partner→DBT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LINC01943 →	-0.774	-0.236	<.001	.005	3	9
OV	EMP3 →	-0.910	-0.596	<.001	<.001	3	8
OV	DSE →	-0.789	-0.504	<.001	<.001	3	7
LSCC	CD80 →	-0.799	-0.339	<.001	<.001	3	7
OV	SLC15A3 →	-1.159	-0.558	<.001	<.001	3	6
OV	STAT1 →	-0.865	-0.441	<.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,687 associations by consensus.

DBT vs LINC01943 — GBM

Explore this scatter interactively →