DBT

Across TCGA cell cohorts, DBT RNA expression is significantly associated with the go_rna of many other GO terms, with 3,857 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DBT-associated GO terms across cancer lineages are Endosomal transport, Metaphase/anaphase transition of cell cycle, and mRNA transport. Each is linked with DBT in more than 15 cancer types. Because this analysis shows association rather than direction, both DBT-to-partner and partner-to-DBT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by DBT-low versus DBT-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DBT→partner) and Y-score (partner→DBT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Endosomal transport →	+0.054	+0.804	<.001	<.001	3	15
OESOPHAGUS	Metaphase/anaphase transition of cell cycle →	+0.179	+0.728	<.001	.005	3	15
OESOPHAGUS	mRNA transport →	+0.135	+0.794	.001	.004	2	16
STOMACH	Positive regulation of mRNA metabolic process →	+0.071	+0.857	<.001	<.001	3	14
STOMACH	Establishment of RNA localization →	+0.102	+0.966	<.001	<.001	3	14
STOMACH	RNA localization →	+0.105	+0.928	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,857 associations by consensus.

Endosomal transport by DBT expression — OVARY

Explore this box plot interactively →