DBP

Across TCGA cell cohorts, DBP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,887 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DBP-associated GO terms across cancer lineages are Maturation of SSU-rRNA, Negative regulation of JUN kinase activity, and Negative regulation of cholesterol efflux. Each is linked with DBP in more than 8 cancer types. Because this analysis shows association rather than direction, both DBP-to-partner and partner-to-DBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of SSU-rRNA grouped by DBP-low versus DBP-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DBP→partner) and Y-score (partner→DBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Maturation of SSU-rRNA →	-0.105	-1.229	.001	<.001	3	8
SOFT_TISSUE	Negative regulation of JUN kinase activity →	+0.089	+1.440	.003	<.001	3	8
STOMACH	Negative regulation of cholesterol efflux →	+0.205	+1.327	<.001	<.001	2	9
UPPER_AERODIGESTIVE_TRACT	Pyrimidine nucleotide transport →	+0.144	+1.029	.006	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of reproductive process →	-0.082	-1.442	<.001	<.001	3	8
KIDNEY	Negative regulation of chromosome condensation →	+0.125	+1.195	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,887 associations by consensus.

Maturation of SSU-rRNA by DBP expression — URINARY_TRACT

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