DBN1

Across TCGA pan-cancer cohorts, DBN1 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated DBN1 data layer compared with 24 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher DBN1 Mutation is associated with better overall survival. In most high-consensus cancer types, elevated DBN1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, CESC, and BLCA are the cancer types where DBN1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	II,III,IV	1.000	0.463	.020	22	view →
CESC	OS	Median	All	0.610	0.877	.001	16	view →
BLCA	OS	Median	IV	0.051	0.600	<.001	12	view →
SARC	DFS	Median	All	0.101	0.632	.011	6	view →
LIHC	OS	Median	III,IV	0.270	0.732	.021	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

DBN1–UCEC (OS)

Open the UCEC breakdown →