DBN1

Across TCGA cell cohorts, DBN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,173 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DBN1-associated GO terms across cancer lineages are Positive regulation of synaptic plasticity, DNA-templated transcription initiation, and Protein-DNA complex assembly. Each is linked with DBN1 in more than 16 cancer types. Because this analysis shows association rather than direction, both DBN1-to-partner and partner-to-DBN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of synaptic plasticity grouped by DBN1-low versus DBN1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DBN1→partner) and Y-score (partner→DBN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of synaptic plasticity →	+0.171	+1.886	.001	.002	2	17
STOMACH	DNA-templated transcription initiation →	+0.102	+3.460	<.001	<.001	3	16
STOMACH	Protein-DNA complex assembly →	+0.078	+3.482	<.001	<.001	3	15
BONE	Protein-DNA complex organization →	+0.091	+1.172	.004	.007	3	15
STOMACH	Establishment of RNA localization →	+0.129	+2.495	<.001	<.001	3	14
STOMACH	Transcription initiation at RNA polymerase II promoter →	+0.067	+2.900	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,173 associations by consensus.

Positive regulation of synaptic plasticity by DBN1 expression — URINARY_TRACT

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