DBH

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DBH RNA expression is significantly associated with the protein abundance of many other proteins, with 8,866 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DBH-associated proteins across cancer lineages are LACTB, SARDH, and COTL1. Each is linked with DBH in more than 4 cancer types. Because this analysis shows association rather than direction, both DBH-to-partner and partner-to-DBH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DBH versus LACTB in LSCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DBH→partner) and Y-score (partner→DBH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCLACTB →+0.408+0.507<.001<.00135
GBMSARDH →+0.575+0.318<.001<.00135
BRCACOTL1 →+0.477+0.481<.001<.00135
HNSCDEF6 →+0.364+0.389<.001<.00135
OVDOCK11 →+0.495+0.334<.001.00235
LSCCLPXN →+0.644+0.605<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,866 associations by consensus.

DBH vs LACTB — LSCC

Per-sample scatter of DBH vs LACTB in LSCC (Pearson r = 0.43).

Explore this scatter interactively →

Exploration