DBF4P3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DBF4P3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,309 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DBF4P3-associated GO terms across cancer lineages are Activation of innate immune response, Regulation of proteolysis involved in protein catabolic process, and DNA-templated transcription elongation. Each is linked with DBF4P3 in more than 7 cancer types. Because this analysis shows association rather than direction, both DBF4P3-to-partner and partner-to-DBF4P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Activation of innate immune response grouped by DBF4P3-low versus DBF4P3-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DBF4P3→partner) and Y-score (partner→DBF4P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCAActivation of innate immune response →+0.072+0.050<.001<.00138
ESCARegulation of proteolysis involved in protein catabolic process →+0.084+0.044<.001.00438
STADDNA-templated transcription elongation →+0.087+0.042<.001.00138
STADVacuolar transport →+0.081+0.064<.001<.00138
STADRegulation of cell projection assembly →+0.067+0.043<.001.00138
STADSubtelomeric heterochromatin formation →+0.066+0.058<.001.00238
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,309 associations by consensus.

Activation of innate immune response by DBF4P3 expression — ESCA

Box plot of Activation of innate immune response in DBF4P3-low vs DBF4P3-high samples in ESCA.

Explore this box plot interactively →

Exploration