DBET

Across TCGA pan-cancer cohorts, DBET RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated DBET data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher DBET RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DBET expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

DLBC, HNSC, and STAD are the cancer types where DBET RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Median	IV	0.417	1.000	.013	42	view →
HNSC	OS	Median	II,III,IV	0.758	0.601	.001	36	view →
STAD	OS	Tertile	II,III,IV	0.568	0.712	.010	28	view →
UCS	DFS	Quartile	All	0.226	0.575	.002	18	view →
PRAD	DFS	Median	All	0.828	0.933	<.001	18	view →
SKCM	DFS	Quartile	II,III,IV	0.806	0.617	.015	16	view →
CHOL	DFS	Tertile	II,III,IV	0.158	0.614	.033	15	view →
LGG	DFS	Median	All	0.752	0.878	<.001	15	view →
KICH	OS	Quartile	III,IV	0.106	0.816	.004	10	view →
PAAD	OS	Median	All	0.611	0.263	.016	10	view →
ACC	DFS	Tertile	All	0.937	0.654	.034	9	view →
LIHC	OS	Tertile	All	0.836	0.723	.021	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

DBET–DLBC (OS)

Open the DLBC breakdown →