DAZAP2

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, DAZAP2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated DAZAP2 data layer compared with 21 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher DAZAP2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated DAZAP2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CCRCC show a favorable association.

UCEC, HNSC, and CCRCC are the cancer types where DAZAP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSQuartileAll0.8471.000.00522view →
HNSCDFSTertileIII,IV0.8100.185.00618view →
CCRCCOSMedianIV1.0000.202.03411view →
PDACOSMedianII,III,IV0.7440.892.0179view →
GBMDFSQuartileAll0.4260.279.0352view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration