DAZAP1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, DAZAP1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DAZAP1 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher DAZAP1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated DAZAP1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

LUAD, CCRCC, and HNSC are the cancer types where DAZAP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADOSQuartileAll0.9440.677.00631view →
CCRCCDFSMedianAll0.7080.900.00512view →
HNSCDFSMedianIII,IV0.9160.988.0412view →
LSCCDFSTertileII,III,IV0.8150.550.0472view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DAZAP1–LUAD (OS)

Kaplan–Meier survival curve for DAZAP1 mass-spec protein-high vs -low samples in LUAD.

Open the LUAD breakdown →

Exploration