DAZAP1

Across TCGA patient cohorts, DAZAP1 mutation is significantly associated with the RNA expression of many other genes, with 3,277 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DAZAP1-associated genes across cancer lineages are CPLX3, PACS2, and MEX3D. Each is linked with DAZAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DAZAP1-to-partner and partner-to-DAZAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CPLX3 grouped by DAZAP1-low versus DAZAP1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAZAP1→partner) and Y-score (partner→DAZAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	CPLX3 →	+0.009	+4.020	<.001	.009	3	2
UCEC	PACS2 →	+0.426	+2.617	.002	.005	3	2
UCEC	MEX3D →	+0.892	+3.721	<.001	<.001	3	2
UCEC	NELFB →	+0.519	+3.637	.002	.001	3	2
UCEC	RNA5SP415 →	+0.632	+2.614	<.001	.001	3	2
UCEC	MIR6803 →	+0.161	+4.571	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,277 associations by consensus.

CPLX3 by DAZAP1 expression — CESC

Explore this box plot interactively →